Dataset from Ciprofloxacin or Tamsulosin in Men With Chronic Prostatitis/Chronic Pelvic Pain Syndrome: a Randomized, Double-blind Trial

Although the cause of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is unknown,
physicians sometimes try to treat it with antibiotics or alpha-receptor blockers.

In this multicenter, double-blind factorial trial, 196 men with moderately severe CP/CPPS
were randomly assigned to 6 weeks of treatment with ciprofloxacin, tamsulosin, both drugs, or
placebo. Neither ciprofloxacin nor tamsulosin substantively reduced symptoms.

Ciprofloxacin and tamsulosin were not effective treatments for CP/CPPS. Patients had
long-standing, refractory CP/CPPS and received trial treatments for only 6 weeks. Patients
with new diagnoses who are given longer courses of the trial treatments might respond
differently.