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Linking oncogenic signaling to transcriptional changes by epigenomic data in a cell line model of human glioblastoma

ChEBI2013-01-01 更新2026-07-21 收录

胶质母细胞瘤机制

表观遗传与转录调控

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-36900 数据链接链接失效反馈

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资源简介：

Linking oncogenic signaling to transcriptional changes by epigenomic data in a cell line model of human glioblastoma

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创建时间：

2013-01-01

胶质母细胞瘤机制

单细胞RNA测序

We used single cell RNA sequencing (scRNA-seq) to analysis the cellular state of organoids harboring different genetic mutations scRNA-sequencing data for 1- and 4-month-old WT (wildtype), PT (PTEN-/-

NIAID Data Ecosystem60

Three-dimensional regulatory hubs support oncogenic programs in glioblastoma [HiChIP]

基因组调控

胶质母细胞瘤机制

Enhancer-promoter communication in the context of the three-dimensional (3D) nucleus is critical for the regulation of transcriptional programs specific for cell identity. Here, we profile the 3D enha

NIAID Data Ecosystem40

Table_1_Temozolomide Treatment Induces HMGB1 to Promote the Formation of Glioma Stem Cells via the TLR2/NEAT1/Wnt Pathway in Glioblastoma.DOCX

胶质母细胞瘤机制

Wnt信号通路调控

Formation of glioma stem cells (GSCs) is considered as one of the main reasons of temozolomide (TMZ) resistance in glioma patients. Recent studies have shown that tumor microenvironment-derived signal

NIAID Data Ecosystem20

Genome-wide transcriptomic analysis in pediatric glioblastomas cell lines by RNA-seq.. Genome-wide transcriptomic analysis in pediatric glioblastomas cell lines by RNA-seq.

胶质母细胞瘤机制

转录组分析

We identified that RACK7 recognizes the histone H3.3G34R mutaion in vitro and in vivo. In order to explore the function of RACK7 and H3.3G34R mutaion, we used three pediatric glioblastomas(pGBM) cell

NIAID Data Ecosystem40

Additional file 8: Figure S5-S7. of Knockdown of NAT12/NAA30 reduces tumorigenic features of glioblastoma-initiating cells

胶质母细胞瘤机制

肿瘤代谢

Figure S5. NAT12/NAA30 knockdown resulted in dysregulation of ribosome assembly as shown by microarray analysis. Using the DAVID functional annotation tool we analyzed the KEGG pathway “Ribosome” wher

Figshare2017-02-21 更新30

Linking oncogenic signaling to transcriptional changes by epigenomic data in a cell line model of human glioblastoma

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