Crystal structure of mutant human geranylgeranyl pyrophosphate synthase (Y246D) in complex with bisphosphonate inhibitor FV0109
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Crystal structure of mutant human geranylgeranyl pyrophosphate synthase (Y246D) in complex with bisphosphonate inhibitor FV0109 Descriptor: Geranylgeranyl pyrophosphate synthase, {[(2-{3-[(4-fluorobenzene-1-carbonyl)amino]phenyl}thieno[2,3-d]pyrimidin-4-yl)amino]methylene}bis(phosphonic acid) Authors: Park, J, Bin, X, Vincent, F, Tsantrizos, Y.S, Berghuis, A.M. Deposit date: 2018-01-15 Release date: 2018-09-05 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Unraveling the Prenylation-Cancer Paradox in Multiple Myeloma with Novel Geranylgeranyl Pyrophosphate Synthase (GGPPS) Inhibitors. J. Med. Chem., 61, 2018
创建时间：
2018-01-15
