BRD2 modulated genes in ISO-induced cardiac hypertrophy
收藏NIAID Data Ecosystem2026-03-13 收录
官方服务:
资源简介:
BRD2 modulated genes in ISO-induced cardiac hypertrophy
应用场景:
创建时间:
2022-04-22
相关数据集
Gene expression profiling by RNA-seq in hTert-HME1 cell line treated with control or BRCA2 siRNAs and grown with or without EGF (epithelial growth factor). Gene expression profiling by RNA-seq in hTert-HME1 cell line treated with control or BRCA2 siRNAs and grown with or without EGF (epithelial growth factor)
Mammary epithelial cells were treated with control or BRCA2 siRNAs, then allowed to recover for 4 passages, then grown in mammary epithelial growth media supplemented with or without EGF (epithelial g
NIAID Data Ecosystem70
The functional impact of BRCA1 BRCT domain variants using multiplexed DNA double-strand break repair assays
In this study, we used multiplexed DNA repair assays of variants in the BRCA1 carboxy-terminus to functionally characterize 2271 variants for homology-directed repair function (HDR) and 1427 varian
NIAID Data Ecosystem30
DataSheet_1_Yeast as a Model to Unravel New BRCA2 Functions in Cell Metabolism.docx
Mutations in BRCA2 gene increase the risk for breast cancer and for other cancer types, including pancreatic and prostate cancer. Since its first identification as an oncosupressor in 1995, the best-c
NIAID Data Ecosystem20
Comprehensive Genomic Analysis of a BRCA2 Deficient Human Pancreatic Cancer
Capan-1 is a well-characterised BRCA2-deficient human cell line isolated from a liver metastasis of a pancreatic adenocarcinoma. Here we report a genome-wide assessment of structural variations and hi
NIAID Data Ecosystem60
A multiplexed homology-directed DNA repair assay reveals the impact of over 1,000 BRCA1 missense substitution variants on protein function
Here we describe a multiplex HDR reporter assay to concurrently measure the effects of hundreds of variants of BRCA1 for their role in DNA repair. Using this assay, we characterized the effects of 1,0
NIAID Data Ecosystem20



