Crystal structure of human Beta-secretase complexed with L-L000430,469
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Crystal structure of human Beta-secretase complexed with L-L000430,469 Descriptor: 3-BENZOYL-N-[(1S,2R)-1-BENZYL-3-(CYCLOPROPYLAMINO)-2-HYDROXYPROPYL]-5-[METHYL(METHYLSULFONYL)AMINO]BENZAMIDE, Beta-secretase 1 Authors: Stachel, S.J, Coburn, C.A, Steele, T.G, Crouthamel, M.-C, Pietrak, B.L, Lai, M.-T, Holloway, M.K, Munshi, S.K, Graham, S.L, Vacca, J.P. Deposit date: 2005-10-10 Release date: 2005-12-06 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Conformationally biased P3 amide replacements of beta-secretase inhibitors. Bioorg.Med.Chem.Lett., 16, 2006
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2005-10-10
