dbEM

dbEM is a database of epigenetic modifiers curated from cancerous and normal genomes. It is created to study role of epigenetic proteins in oncogenesis and cancer drug resistance. This database maintain genomic information about each epigenetic modifier like mutations, copy number variation and gene expression in thousand of tumor samples, cancer cell lines and healthy individuals; obtained from COSMIC, CCLE and human thousand-genome project.

搜集汇总

背景与挑战

背景概述

dbEM是一个专注于表观遗传修饰因子的数据库，收集了来自癌性和正常基因组的表观遗传蛋白信息，旨在研究其在肿瘤发生和癌症耐药性中的作用。该数据库整合了COSMIC、CCLE和千人基因组计划等来源的数据，提供了突变、拷贝数变异和基因表达等基因组信息，覆盖数千肿瘤样本、癌细胞系和健康个体。