Additional file 6: Table S5. The methylation loci and corresponding genes involved in MAPK signalling, pyruvate metabolism, glycolysis, and proteoglycan pathways.
Osteosarcoma is the most frequent bone tumor. Notwithstanding that significant medical progress has been achieved in recent years, the 5-year overall survival of osteosarcoma patients is inferior. Reg
Since loss of the NF2 tumor suppressor gene results in p21-activated kinase (Pak) activation, PAK inhibitors hold promise for the treatment of NF2-deficient tumors. To test this possibility, we asked
