Endometrial miRNA-seq at different stages of endometrosis and early pregnancy in mare

Endometrosis is a degenerative chronic condition of the equine uterus, defined as a fibrosis process that develops around the endometrial glands and in the stroma. Equine endometrosis causes changes in endometrium structure as well as in the uterine microenvironment and the consequence leads to early pregnancy loss. We compared the miRNA profile of mare endometrium: (1) at different stages of endometrosis in the follicular phase of the estrus cycle and (2) at the mid-luteal stage of the estrous cycle with 25-28 days of pregnancy using microRNA-sequencing.