five

DNA context surrounding the novel junctions.

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NIAID Data Ecosystem2026-03-12 收录
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https://figshare.com/articles/dataset/DNA_context_surrounding_the_novel_junctions_/16440756
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The novel DNA junctions identified in the two lines (POP33_31 = 12, POP30_88 = 14) exhibiting clustered patterns are preferentially located in regions that are rich in gene sequences and poor in repeated sequences, compared to the rest of the genome. Enrichment ratio represents the comparison between the means of genomic feature density at real breakpoints and the means of a similar set of randomly selected features. Ratio >1 indicates validated breakpoints that have a higher density of features than the genome average, while ratio <1 indicates the lower density of validated breakpoints compared to the genome. Genes are enriched near breakpoints of both lines with 100kb-window size (POP33_31 p<0.001; POP30_88 p<0.05). The lack of repeated elements surrounding breakpoints are observed in both lines as well (POP33_31 p<0.001; POP30_88 p<0.001). (XLSX)
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2021-08-25
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