Dataset used in paper ‘Evaluation of [13N]ammonia positron emission tomography as a potential method for quantifying glutamine synthetase activity in the human brain.’ (Egerton A and Dunn JT et al 2020)

Dynamic PET & structural MRI images with accompanying blood sample data for repeatability study investigating human cerebral ammonia metabolism with 15O-H2O and 13N-NH3 PET tracers. Data from eight healthy subjects. Each subject had a 15O-H2O PET-CT brain scan followed by a 13N-NH3 scan; both scans repeated same day. Continuous and manual arterial blood sampling was acquired on all scans, with metabolite analysis on the NH3 scan blood manual samples. This data was used in the paper: “Evaluation of [13N]ammonia positron emission tomography as a potential method for quantifying glutamine synthetase activity in the human brain” by Egerton A and Dunn JT et al in EJNMMI Research.

动态正电子发射断层扫描（PET）与结构磁共振成像（MRI）图像及其伴随的血样数据，用于研究人体大脑氨代谢的重复性研究，其中采用了15O-H2O和13N-NH3 PET示踪剂。数据来源于八名健康受试者。每位受试者均接受了一次15O-H2O PET-CT脑部扫描，随后进行13N-NH3扫描；两次扫描均在同一天完成。在所有扫描过程中均进行了连续及手动动脉血样采集，并在13N-NH3扫描血样中进行了代谢物分析。这些数据被用于Egerton A和Dunn JT等人在EJNMMI Research上发表的论文《[13N]氨正电子发射断层扫描作为量化人脑谷氨酰胺合成酶活性的潜在方法的评估》。