Supplementary materials for "Trends, age–period–cohort patterns and attributable cardiovascular–kidney–metabolic risks of ischemic heart disease in five East Asian countries, 1990–2023: A systematic analysis of the Global Burden of Disease Study 2023"

Supplementary tables and figures accompanying the article "Trends, age–period–cohort patterns and attributable cardiovascular–kidney–metabolic risks of ischemic heart disease in five East Asian countries, 1990–2023: A systematic analysis of the Global Burden of Disease Study 2023", submitted to Advances in Clinical and Experimental Medicine. The package contains the following files: Supplementary Table 1. Segment-specific annual percent change in the age-standardized DALY rate for ischemic heart disease, 1990–2023. Supplementary Table 2. Country-specific age–period–cohort estimates for the ischemic heart disease DALY rate, 1994–2023: local drifts, net drift, period rate ratios and cohort rate ratios. Supplementary Table 3. Risk-attributable age-standardized DALY rate (per 100 000) of ischemic heart disease, 1990 and 2023, compared with the change in the total rate. Supplementary Table 4. Age-specific population-attributable fraction (%) of ischemic heart disease DALYs for five component risks, by country, 2023. Supplementary Table 5. Mean absolute SHAP values of the five component risks in the gradient-boosted model, 1990–2023 country–year panel. Supplementary Table 6. Leave-one-country-out stability of mean absolute SHAP values in the gradient-boosted model. Supplementary Table 7. Multivariable negative binomial regression of annual ischemic heart disease DALY counts on the five component-risk PAFs. Supplementary Table 8. Univariable negative binomial regressions of annual ischemic heart disease DALY counts on each component-risk PAF. Supplementary Table 9. Selected exponential smoothing models and training-set diagnostics for the age-standardized DALY rate of ischemic heart disease, 1990–2023. Supplementary Fig. 1. Age-specific and cohort-specific DALY rates for ischemic heart disease by country, 1994–2023. Supplementary Fig. 2. Age, period and cohort deviations from the country-specific age–period–cohort models, 1994–2023. Supplementary Fig. 3. Sex-specific age profiles of the ischemic heart disease DALY rate in 2023. Supplementary Fig. 4. Time trends in risk attribution and change in risk-attributable burden, 1990–2023. Supplementary Fig. 5. Short-term projections of the age-standardized DALY rate for ischemic heart disease to 2030. Supplementary Fig. 6. Age-standardized DALY rate for ischemic heart disease in 2023 against the Socio-demographic Index.