Supplementary Table 1 Chemicals and Reagents

Glucose transporter-1 is known for regulating glucose uptake in brain endothelial cells. This study used global transcriptome analysis and diabetic mouse models to reveal the novel role of Glucose transporter-1 in regulating brain endothelial cell homeostasis by reducing the inflammation response and increasing the protection mechanism. Importantly, the Glucose transporter-1-dependent protection mechanism is compromised in diabetic conditions, which explains why diabetic patients have a high risk of cerebrovascular diseases.