Human DNA-methylation data have been used to develop highly accurate biomarkers of aging ("epigenetic clocks"). Recent studies demonstrate that similar epigenetic clocks for mice (Mus Musculus) can be

NIAID Data Ecosystem60

Cell-free DNA methylation patterns in aging and their association with inflamm-aging

衰老生物标志物

表观遗传学分析

Aim: Liquid biopsies analyzing cell-free DNA (cfDNA) methylation in plasma offer a noninvasive diagnostic for diseases, with the potential of aging biomarkers underexplored. Methods: Utilizing enzymat

NIAID Data Ecosystem30

Human age-declined saliva metabolic markers determined by LC-MS

衰老代谢组学

衰老生物标志物

Metabolites in human biofluids reflect individual physiological body states influenced by various factors. Using liquid chromatography-mass spectrometry (LC-MS), we conducted non-targeted, non-invasiv

NIAID Data Ecosystem70

Small RNA sequencing of small extracellular vesicles derived from senescent vs. nonsenescent human dermal fibroblasts (HDFs). Small RNA sequencing of small extracellular vesicles derived from senescent vs. nonsenescent human dermal fibroblasts (HDFs)

细胞外囊泡microRNA

衰老生物标志物

We report small RNA sequencing technology for high-throughput profiling of microRNA content within small extracellular vesicles isolated from nonsenescent and senescent human dermal fibroblasts. Overa

NIAID Data Ecosystem40

Supplemental Figure 1-8

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