Copper(II)-Mediated Chelation-Assisted Regioselective N‑Naphthylation of Indoles, Pyrazoles and Pyrrole through Dehydrogenative Cross-Coupling
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A copper-mediated picolinamide directed regioselective cross-coupling of naphthylamines with azoles is developed via C–H functionalization and C–N bond formation. The reaction of indoles leads to the formation of chiral C–N cross-coupled products with functional group tolerance. These reaction conditions can also be extended to the cross-coupling of pyrazole and pyrrole scaffolds.
创建时间:
2017-04-24



