The concentration of each drug was determined according to which it is administered in clinical practice. SD: Standard Deviation calculated from three independent repeats (n = 3). Selectivity: Drugs c
Pharmacokinetic parameters were calculated after the i.v. injection of free DOX or SCL-DOX in healthy SD rats at a dose of 5 mg/kg. Data are shown as means±S.E. of at least three independent experimen
Pharmacokinetic parameters after oral administration of optimized Eudragit-coated ALS-SLN formula and Fosamax® Tablet (n = 6). The mean difference is significant at the 0.05 level.
