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资源简介：
Antimony resistance marker of 58 kDa | ARM58 Leishmania infantum (strain JPCM5)
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创建时间：
2022-12-06
相关数据集
Comparative IC 50 of meglumine antimoniate and 2HF against L . amazonensis -infected macrophages using wild-type and antimony-resistant L . amazonensis promastigotes.
Comparative IC50 of meglumine antimoniate and 2HF against L. amazonensis-infected macrophages using wild-type and antimony-resistant L. amazonensis promastigotes.
NIAID Data Ecosystem20
Susceptibility to AmB of AmBR L . mexicana axenic promastigotes before and after infection in mice and in infected macrophages.
Values in μM, Mean ± Standard Deviation (SD). One-way ANOVA was performed independently for each compound to determine differences of the mean between groups. Tukey’s multiple compared pairwise differ
NIAID Data Ecosystem20
Amastigote susceptibility (IC50) of the in vitro resistance selection procedure to PMM-MIL combination therapy.
No difference was observed between IC50 of the wild-type strain (LEM3323 WT) and the strains that underwent three (LEM3323 PMM/MIL3) or five (LEM3323 PMM/MIL5) repeated exposures to the combined high
Figshare2017-05-25 更新10
Coding sequence mutations within the LiMT and LiRos3 MIL-transporting complex, identified in the L . infantum MIL-resistant strains.
Coding sequence mutations within the LiMT and LiRos3 MIL-transporting complex, identified in the L. infantum MIL-resistant strains.
NIAID Data Ecosystem20
Multiple Mutations in Heterogeneous Miltefosine-Resistant Leishmania major Population as Determined by Whole Genome Sequencing
BackgroundMiltefosine (MF) is the first oral compound used in the chemotherapy against leishmaniasis. Since the mechanism of action of this drug and the targets of MF in Leishmania are unclear, we gen
Figshare2016-01-18 更新20
