Summary of challenges and solutions.

Suicide is the leading cause of death among children and young people under 35 in the United Kingdom (UK), and suicide rates in this group are rising. Schools are considered an appropriate and logical setting for suicide prevention activities, with universal access to a wide range of young people. However, schools are complex settings, meaning research projects often encounter a number of logistical, engagement, and implementation challenges. This commentary presents learnings from a regionally based feasibility trial of an integrated response to suicide risk among UK secondary schools. We explore the barriers and challenges to engaging and conducting research on suicide and self-harm prevention with young people and offer recommendations for researchers.