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VRK3 depletion in Pontine Diffuse Midline Glioma (DMG)-K27 altered cells

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NIAID Data Ecosystem2026-05-01 收录
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https://www.omicsdi.org/dataset/ega/EGAS00001007047
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In order to investigate possible mechanisms underlying the phenotype of cell fitness decline observed following decrease of VRK3 in pontine DMG-K27 altered cells 7, we examined differences in global gene expression. RNA-seq was performed 44h and 60h post-transduction with two distinct shRNAs targeting VRK3 to be able to evaluate the early impact of VRK3 knock-down (KD) in four independent in vitro models of DMGEGA study EGAS00001007047
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2023-10-03
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