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Crystal Structure of SARS-CoV-2 Main Protease (Mpro) K90R Mutant in Complex with Inhibitor nirmatrelvir

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Protein Data Bank Japan2025-04-09 更新2026-05-09 收录
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Crystal Structure of SARS-CoV-2 Main Protease (Mpro) K90R Mutant in Complex with Inhibitor nirmatrelvir Descriptor: (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide, 3C-like proteinase Authors: Lin, M, Liu, X. Deposit date: 2023-03-10 Release date: 2024-03-13 Last modified: 2025-04-09 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Molecular mechanism of ensitrelvir inhibiting SARS-CoV-2 main protease and its variants. Commun Biol, 6, 2023
创建时间:
2023-03-10
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