Peritoneal metastasis (PM) is diagnosed in almost half of patients with advanced gastric cancer (GCa) and has a very poor prognosis. However, the molecular mechanisms of PM in GCa remain poorly unders

NIAID Data Ecosystem20

RNA sequence of gastric cancer with malignant ascites [RNA-seq]

胃癌腹膜转移

转录组分析

Gastric cancer is one of the leading causes of cancer mortality worldwide, and peritoneal metastasis is a hallmark of incurable advanced gastric cancer. The identification of molecular vulnerability f

NIAID Data Ecosystem30

Gastric cancer CAFs maintain SASP through epigenetic histone modification and enhance peritoneal metastasis

胃癌腹膜转移

肿瘤微环境表观遗传调控

Secreted factors from cancer associated fibroblast (CAFs) showing senescence-associated secretory phenotype (SASP) is likely to be implicated in cancer progression, but the precise mechanism is not fu

NIAID Data Ecosystem20

Phase I PIANO Trial

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