The genes involved in EMT.

The majority of the genes' expressions, except GSC, TJP1 and MMP3, indicate further malignant development of the early onset cancer group. Surprisingly, E-cadherin was down-regulated by more than 5 fold in the cancer patients.1The value is the median of log2-scaled expressions of the group.2The value is the fold-change of the cancer samples over the healthy controls.3The genes refer to Knutson et al. [36].4The genes refer to Polyak et al. [9].5It is the normal-appearing mucosa in the CRC patients.