Crystal structure of human PI3K-gamma in complex with a pyridyl-triazine inhibitor
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Crystal structure of human PI3K-gamma in complex with a pyridyl-triazine inhibitor Descriptor: 4-(2-[(6-methoxypyridin-3-yl)amino]-5-{[4-(methylsulfonyl)piperazin-1-yl]methyl}pyridin-3-yl)-6-methyl-1,3,5-triazin-2-amine, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, SULFATE ION Authors: Whittington, D.A, Tang, J, Yakowec, P. Deposit date: 2012-02-03 Release date: 2012-05-16 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.95 Å) Cite: Structure-based design of a novel series of potent, selective inhibitors of the class I phosphatidylinositol 3-kinases. J.Med.Chem., 55, 2012
创建时间：
2012-02-03
