Mouse P10 cerebellum: Smarca5 conditional KO mice (cKO) versus wild type controls

Gene expression profiling of mouse cerebellum in which the experimental strain conditionally lack the Smarca5 gene that encodes for the catalytic subunit of multiple chromatin remodeling complexes. Deletion of Smarca5 was restricted to those cells expressing Cre-recombinase driven by the Nestin promoter. Comparison of gene expression in P10 cerebella of Smarca5 cKO mice versus wild type controls. Three samples of each strain were used in a total of 3 replicates.本数据集针对实验品系小鼠小脑开展基因表达谱分析，该实验品系的Smarca5基因发生条件性缺失——该基因编码多种染色质重塑复合物的催化亚基。Smarca5基因的缺失仅局限于由Nestin启动子驱动表达Cre重组酶（Cre-recombinase）的细胞中。本研究比较了Smarca5条件性敲除（cKO）小鼠与野生型对照小鼠在出生后第10天（P10）的小脑组织的基因表达差异。每个品系采用3份样本，共计完成3次重复实验。