Expression data from epidermal samples. Homo sapiens

Gene expression profiling of epidermal samples obtained from sun-exposed and sun-protected body sites from younger (60 years old) individuals. The Affymetrix U133A plus 2.0 array was used to obtain gene expression data. Samples included 4 younger sun exposed epidermal samples, 4 older sun exposed epidermal samples, 3 younger sun protected epidermal samples, 5 older sun protected epidermal samples. Overall design: To determine how gene expression relates to identified methylation changes with aging and sun-exposure, RNA was extracted from dispase separated epidermal samples and analyzed using Affymetrix U133A plus 2.0 arrays.