Nickel-Catalyzed Decarbonyloxidation of 3‑Aryl Benzofuran-2(3H)‑ones to 2‑Hydroxybenzophenones
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We have developed a protocol to facilitate the nickel-catalyzed decarbonyloxidation of 3-aryl benzofuran-2(3H)-ones to 2-hydroxybenzophenones under mild conditions, which is an efficient approach for the decarbonyloxidation of lactones in organic synthesis. A diverse range of substrates can undergo C(O)–O/C(O)–C bond cleavage to generate the target products in good yields. These 2-hydroxybenzophenones can be converted into a variety of compounds via reactions such as esterification, cyclization, and reduction.
创建时间：
2020-06-02
