Computational studies have given a great contribution in building our current understanding of the complex behavior of protein molecules; nevertheless, a complete characterization of their free energy
The success of any physical model critically depends upon adopting an appropriate representation for the phenomenon of interest. Unfortunately, it remains generally challenging to identify the essenti
Particles are marked as in Fig. 3A: phosphates P1 and P2 belong to one DNA strand; P3 and P4 belong to the other strand; P′1–P′4 are phosphates from the next unit (see Fig. 3).
The nucleosome core particle (NCP) is a large complex of 145–147 base pairs of DNA and eight histone proteins and is the basic building block of chromatin that forms the chromosomes. Here, we develop