Low-coverage single-cell mRNA sequencing reveals cellular heterogeneity and activated signaling pathways in developing cerebral cortex.
收藏NIAID Data Ecosystem2026-05-02 收录
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The authors captured 301 single cells from 11 populations using microfluidics and analyzing single-cell transcriptomes across downsampled sequencing depths. They demonstrate that shallow single-cell mRNA sequencing (∼50,000 reads per cell) is sufficient for unbiased cell-type classification and biomarker identification in the developing cortex.
创建时间：
2025-02-14
