RNA-seq of the colon of TG pigs
收藏NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP579622
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资源简介：
Understanding the characteristics and pathogenesis of intestinal diseases under metabolic disorders is crucial for developing effective interventions. Here we successfully constructed a transgenic (TG) Bama pig model using CRISPR/Cas9 technique by knocking in three humanized risk susceptibility genes. TG pigs were also administered a high-fat and high-sugar diet (HFHSD) for 4, 8, and 12 months to accelerate the progression of metabolic disorders.Transcriptomic sequencing was performed to assess the colonic function in TG pigs.
创建时间：
2025-07-01
