Barcoded-Influenza A virus raw sequence reads for K153E library. Influenza A virus isolate:CA07

This study seeks to characterize viral populations and bottlenecks during in vivo infections in animal models. We used 10-nt barcodes embedded into influenza A viruses (IAV) to demonstrate infection dynamics of these viruses in mice and ferrets, quantifying population composition at previously unattainable resolution, and determining the nature of bottlenecks during infection. This BioProject contains data regarding our re-designed barcoded-IAV with a K153E mutation inserted to avoid tissue culture-induced skewing of our barcodes.