Metabolic fitness of IgA+ plasma cells in the gut requires DOCK8

NIAID Data Ecosystem2026-05-01 收录

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE198847 数据链接链接失效反馈

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DOCK8 is required for T cell-dependent gut IgA by maintaining plasma cell metabolic fitness 16S of v4 region

创建时间：

2024-01-12

Peyer’s Patch Germinal Centers Select Innate-like BCRs

B细胞受体

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Primary B cell receptor (BCR)/antibody variable region exons are generated by V(D)J recombination with junctional diversification creating immensely diverse antigen contact-encoding CDR3s. While most

NIAID Data Ecosystem160

Peyer's Patch Germinal Centers Select Innate-like BCRs

B细胞受体库分析

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Primary B cell receptor (BCR)/antibody variable region exons are generated by V(D)J recombination with junctional diversification creating immensely diverse antigen contact-encoding CDR3s. While most

NIAID Data Ecosystem90

Hippo, TGF-β, and Src-MAPK pathways regulate transcription of the upd3 cytokine in Drosophila enterocytes upon bacterial infection

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细胞信号调控

Cytokine signaling is responsible for coordinating conserved epithelial regeneration and immune responses in the digestive tract. In the Drosophila midgut, Upd3 is a major cytokine, which is induced i

NIAID Data Ecosystem70

Auto-reactivity against gut bacterial peptides in patients with late-onset diabetes

糖尿病

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The depletion of gut mucosal barrier enables exposure of gut microbes/gut microbial products to the host mucosal immunity which may increase the risk of metabolic/inflammatory disorders. These immune

DataCite Commons2021-05-06 更新90

Genetic, Molecular and Physiological Basis of Variation in Gut Immunocompetence

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遗传学

Gut immunocompetence involves immune, stress, and regenerative processes. To investigate the determinants underlying inter-individual variation in gut immunocompetence, we perform enteric infection of

干细胞与再生医学数据中心2022-02-20 更新80

Metabolic fitness of IgA+ plasma cells in the gut requires DOCK8

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