Crystal structure of M. tuberculosis PheRS-tRNA complex bound to inhibitor D-116

Crystal structure of M. tuberculosis PheRS-tRNA complex bound to inhibitor D-116 Descriptor: 1,2-ETHANEDIOL, 1H-benzimidazol-2-amine, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... Authors: Gade, P, Chang, C, Forte, B, Wower, J, Gilbert, I.H, Baragana, B, Michalska, K, Joachimiak, A, Center for Structural Biology of Infectious Diseases (CSBID) Deposit date: 2024-09-26 Release date: 2025-02-12 Last modified: 2025-02-19 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Different chemical scaffolds bind to L-phe site in Mycobacterium tuberculosis Phe-tRNA synthetase. Eur.J.Med.Chem., 287, 2025