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Perturbation of spinal cord gene expression accompany peripheral neuropathy in murine model of type 1 diabetes

ChEBI2022-10-16 更新2026-07-12 收录

神经病变机制

脊髓基因表达

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-12252 数据链接链接失效反馈

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资源简介：

Perturbation of spinal cord gene expression accompany peripheral neuropathy in murine model of type 1 diabetes

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创建时间：

2022-10-16

文献计量学

脊髓基因表达

BackgroundSpinal cord injury (SCI) is a severe disease with motor and sensory function being destroyed, which leads to a poor prognosis and a serious financial burden. It is urgent to figure out the m

NIAID Data Ecosystem320

MicroRNA expression profile of human umbilical vein endothelial cells in response to Coxsackievirus A10 infection

病毒miRNA表达

神经病变机制

Coxsackievirus A10 (CV-A10) constitutes one of the major pathogens of hand, foot, and mouth disease (HFMD), which can cause mild to severe illness and even death. Most of these severe and death cases

NIAID Data Ecosystem90

DNA methylation status of myelinating Schwann cells during development and in diabetic neuropathy [Gene Expression Array: GNMT mice]

细胞DNA甲基化

神经病变机制

DNA methylation is a key epigenetic regulator of mammalian embryogenesis and somatic cell differentiation. Using high-resolution genome-scale maps of methylation patterns, we show that the formation o

NIAID Data Ecosystem70

Rosiglitazone Treatment Reduces Diabetic Neuropathy in STZ treated DBA/2J mice

神经病变机制

药物靶点发现

Diabetic Neuropathy (DN) is a common complication of diabetes. Currently, there is no drug treatment to prevent or slow the development of DN. Rosiglitazone (Rosi) is a potent insulin sensitizer and

NIAID Data Ecosystem110

Enhanced deoxysphingobase production in HSN1 results in sensory nerve toxicity through deficits in both cell autonomous and axoglial signalling, ameliorated by serine treatment

神经病变机制

脂质代谢

Hereditary sensory neuropathy type 1 (HSN1) is caused by mutations in either the SPTLC1 or SPTLC2 sub-units of the enzyme Serine Palmitoyl Transferase resulting in the production of Deoxyshingobases (

NIAID Data Ecosystem70

Perturbation of spinal cord gene expression accompany peripheral neuropathy in murine model of type 1 diabetes

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