Transcriptional profiling of fetal hypothalamic TRH neurons

To our knowledge, this is the first report identifying transcripts with a potentially important role during the development of a specific hypothalamic neuronal phenotype. This genome-scale study forms a rational foundation for identifying genes that might participate in the development and function of hypothalamic TRH neurons.据我们所知，本研究首次鉴定出在特定下丘脑神经元表型发育过程中发挥潜在重要作用的转录本。此项全基因组规模研究为鉴定可能参与下丘脑促甲状腺激素释放激素（TRH）神经元发育与功能的基因奠定了合理基础。