MIC of the SCAR compounds acting on non-replicating persistent (NRPII) MTB H37Rv.

Figshare2015-12-02 更新2026-04-29 收录

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https://figshare.com/articles/dataset/_MIC_of_the_SCAR_compounds_acting_on_non_replicating_persistent_NRPII_MTB_H_37_Rv_/707868 数据链接链接失效反馈

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MIC of the SCAR compounds acting on non-replicating persistent (NRPII) MTB H37Rv.

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2015-12-02

Complete analysis of data from screening for antitubercular activity and physico chemical properties of the hit compounds.

抗结核药物

化合物活性分析

Rifampicin and Isoniazid were taken as controls. MIC values for controls against M. smegmatis are Rif-2.43±0.02μM and Inh-11.03±0.05 μM and H37Rv are Rif-0.08±0.01μM and Inh-0.22±0.3 μM.

NIAID Data Ecosystem60

A competitive activity-based protein profiling platform yields cell wall synthesis inhibitors active against replicating and non-replicating Mycobacterium tuberculosis

抗结核药物

细胞壁生物学

The identification and validation of a small molecule's targets is a major bottleneck in the discovery process for tuberculosis antibiotics. Activity-based protein profiling (ABPP) is an efficient too

NIAID Data Ecosystem40

In vitro evaluation of nine imidazo[2,1-b]thiazole-5-carboxamides, Q203 and BTZ043 against replicating and non-replicating Mtb, cellular toxicity and aqueous solubility determination.

抗结核药物

体内药效评估

In vitro evaluation of nine imidazo[2,1-b]thiazole-5-carboxamides, Q203 and BTZ043 against replicating and non-replicating Mtb, cellular toxicity and aqueous solubility determination.

Figshare2020-01-06 更新30

A novel biosafety level 2 compliant tuberculosis infection model using a Δ leuD Δ panCD double auxotroph of Mycobacterium tuberculosis H37Rv and Galleria mellonella

结核病传播建模

抗结核药物

Mammalian infection models have contributed significantly to our understanding of the host-mycobacterial interaction, revealing potential mechanisms and targets for novel antimycobacterial therapeutic

NIAID Data Ecosystem50

Silica catalyzed one pot synthesis of hybrid thiazolidin-4-one derivatives as anti-tubercular and anti-inflammatory agent by attenuating COX-2 pathway

药物化学

抗结核药物

A novel series of a hybrid class of hybrid thiazolidin-4-one derivatives were designed and synthesized through one-pot catalytic synthesis. The reaction was catalyzed in the presence of silica-H 2

DataCite Commons2020-08-26 更新40

MIC of the SCAR compounds acting on non-replicating persistent (NRPII) MTB H37Rv.

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