首页/数据集/CRISPR screening reveals targets to reprogram long-lived effector CD8+ T cells for cancer therapy.

CRISPR screening reveals targets to reprogram long-lived effector CD8+ T cells for cancer therapy.

NIAID Data Ecosystem2026-03-11 收录

CRISPRi筛选

癌症免疫治疗T细胞重编程

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE126072 数据链接链接失效反馈

官方服务：

资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2019-12-20

相关数据集

raw data for main figures.xlsx

CRISPRi筛选

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data used to create main figures for: Park et. al., Efficient prioritization of CRISPR screen hits by accounting for targeting efficiency of guide RNA, BMC Biol, 2023.

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Bcor loss perturbs myeloid differentiation and promotes leukaemogenesis [TargetedCRISPRscreen]

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Investigating Bcor target genes in BcorΔE9-10KrasG12D leukaemia with a custom CRISPR dropout screen BcorΔE9-10KrasG12D cell line was transduced with a custom CRISPR library and a dropout screen was pe

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Genes of CRISPR-Cas9 negative screening.

CRISPRi筛选

肿瘤免疫逃逸

We compared changes in sgRNA abundance between T24 cells challenged and unchallenged by CD8+ T cells, and then performed negative screening (p < 0.01, log2Fold change < −1.0, and good sgRNAs ≥ 5). (X

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Genome-wide CRISPR/Cas9 loss-of-function screen for prostate cancer cell line. Genome-wide CRISPR/Cas9 loss-of-function screen for prostate cancer cell line

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前列腺癌联合治疗

Prostate cancer (PCa) is the most frequently diagnosed malignancy in men worldwide. Epigenetic regulation has been recognized as a main mechanism of cancer evolution. PRMT5 is the major type II protei

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Essential gene profiles for human pluripotent stem cells identify uncharacterized genes and substrate dependencies. Mair et al.

干细胞鉴定

CRISPRi筛选

Human pluripotent stem cells (hPSCs) provide an invaluable tool for modeling diseases and hold promise for regenerative medicine. For understanding pluripotency and lineage differentiation mechanisms,

NIAID Data Ecosystem20