MediaDB

MediaDB collects chemically defined growth media from primary literature sources for fully sequenced organisms. The database is maintained by the Price Lab at the Institute for Systems Biology. MediaDB places special emphasis on organisms with existing genome scale metabolic models (for examples of such models, visitors can refer to the list of in silico organisms maintained by the Systems Biology Research Group at UC San Diego). Information collected in MediaDB is intended to aid in formulating defined media, discovering connections between media compounds and organism characteristics, and reconstructing genome-scale metabolic networks.MediaDB 从原始文献中收录了面向完成全基因组测序的生物（fully sequenced organisms）的化学成分明确的生长培养基（chemically defined growth media）。该数据库由系统生物学研究所（Institute for Systems Biology）的普莱斯实验室（Price Lab）负责维护。MediaDB 特别聚焦于已构建基因组规模代谢模型（genome scale metabolic models）的生物；若需了解此类模型的示例，访问者可查阅加州大学圣地亚哥分校(UC San Diego)系统生物学研究组（Systems Biology Research Group）维护的虚拟生物（in silico organisms）列表。MediaDB 所收录的信息旨在助力明确型培养基的配方研发、培养基组分与生物特性间关联的挖掘，以及基因组规模代谢网络（genome-scale metabolic networks）的重构。

搜集汇总

背景与挑战

背景概述

MediaDB是一个收集全基因组测序生物化学定义生长培养基的数据库，特别关注已有基因组尺度代谢模型的生物。该数据库由系统生物学研究所的Price Lab维护，旨在辅助配制定义培养基、探索化合物与生物特征关联以及重建代谢网络。