Transcriptional control by Merlin of contact inhibition and tissue homeostasis

ChEBI2015-04-01 更新2026-07-21 收录

细胞接触抑制

Merlin蛋白功能

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-53501 数据链接链接失效反馈

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Transcriptional control by Merlin of contact inhibition and tissue homeostasis

创建时间：

2015-04-01

Gene expression signature regulated by cell density and Merlin/NF2 knockdown in HMLE cells

细胞接触抑制

基因表达调控

Merlin has been implicated in contact-dependent inhibition of proliferation To define genes regulated by Merlin and study their relationship to cell density-dependent gene expression, microarray exper

NIAID Data Ecosystem60

RNA-sequencing in for Low, high or high density+PTPRK-deleted HeLa cells

细胞接触抑制

PTPRK功能研究

Density-dependent regulation of cell growth is presumed to be caused by cell-cell contact, but the underlying molecular mechanism is not yet clearly defined. Our goal is to identify receptor-type prot

NIAID Data Ecosystem50

p190 RhoGAP mediates contact inhibition of cell proliferation by repressing YAP1-mediated gene transcription. Canis lupus familiaris

细胞接触抑制

Hippo信号通路

Recently, ARHGAP35 encoding p190A RhoGAP was unexpectedly found to rank among the 20-30 most frequently mutated genes in human cancer. The spectrum of mutations in ARHGAP35 is consistent with that of

NIAID Data Ecosystem30

Confluent versus Sub-confluent HUVEC. Homo sapiens

内皮细胞转录组

细胞接触抑制

HUVEC (N=3 isolates) were separately grown to sub-confluency, and to confluency. In order to study the effects of growth and contact inhibition on the transcriptome, the microarray gene expression pro

NIAID Data Ecosystem50

Development of gene expression signatures for contact-inhibited and adipogenic-differentiated 3T3-L1 and NIH3T3 fibroblasts

细胞接触抑制

脂肪形成分化

Given previous works showing that, in the process of adipogenic differentiation of 3T3-L1 fibroblasts, the cells need to be cultured to confluency followed by additional incubation before initiating d

NIAID Data Ecosystem40

Transcriptional control by Merlin of contact inhibition and tissue homeostasis

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