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Inactivation of the histone H3 K36 methyltransferase NSD1 confers resistance to EZH2 inhibition

NIAID Data Ecosystem2026-05-01 收录

表观遗传学耐药机制

药物靶点研究

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE178490 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2023-10-26

基因表达调控

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Afatinib在食管癌中的抑制作用的数据

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食管癌治疗疗效

Afatinib在食管癌中的抑制作用的数据，有助于食管癌治疗靶点发现及新药研究。此数据条目，来源于实验室检测，按照相关规范和标准加工处理，支撑数据采集者的论文发表，可在符合科学规范及学术道德标准的前提下，仅供药理学相关领域从事科研、发表论文论著、制定标准、支撑服务等工程技术人员使用

国家人口健康科学数据中心60

Summary of the drug characterization at target level.

药物靶点研究

物质特征分析

Summary of the drug characterization at target level.

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Crystal Structure of B-cell lymphoma 6 protein BTB domain in complex with ligand 9 at 12.78 MGy X-ray dose.

蛋白质晶体学

药物靶点研究

Crystal Structure of B-cell lymphoma 6 protein BTB domain in complex with ligand 9 at 12.78 MGy X-ray dose.

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Activator-Bound Structure of Human Pyruvate Kinase M2

酶结构解析

药物靶点研究

Activator-Bound Structure of Human Pyruvate Kinase M2 Descriptor: 1,6-di-O-phosphono-beta-D-fructofuranose, 1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-4-[(4-methoxyphenyl)sulfonyl]piperazine, L(+)-T

Protein Data Bank Japan2023-09-06 更新50

Inactivation of the histone H3 K36 methyltransferase NSD1 confers resistance to EZH2 inhibition

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