Structure of NUDT15 in complex with TH7755
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Structure of NUDT15 in complex with TH7755 Descriptor: (R)-6-((2-methyl-4-(1-methyl-1H-indole-5-carbonyl)piperazin-1-yl)sulfonyl)benzo[d]oxazol-2(3H)-one, MAGNESIUM ION, Probable 8-oxo-dGTP diphosphatase NUDT15 Authors: Rehling, D, Stenmark, P. Deposit date: 2020-12-07 Release date: 2021-03-24 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Crystal structures of NUDT15 variants enabled by a potent inhibitor reveal the structural basis for thiopurine sensitivity. J.Biol.Chem., 296, 2021
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2020-12-07
