Plasma iron in µg/dL, non-heme tissue iron content in µg iron/g dry tissue. (A) Female wild-type and Hfe−/− mice. n = 5–7 per group. ‡P≤0.005 versus WT control mice; ⧫P≤0.001 versus LPS-treated WT mic
This experiment compared aRNA derived from the kidney inner medula of three mice lacking a functional aquaporin-1 gene to three wild type mice. Each sample was hybridized 4 times, against 4 of the oth
We found that global heterozygous midnolin knockout attenuated the severity of nonalnonalcoholic fatty liver disease (NAFLD) in mice fed a Western-style diet, high in fat, cholesterol, and fructose. T