Surgical site infection (SSI) 16S rRNA amplicon sequencing

Surgical site infections (SSIs) are common in colorectal surgery. Mechanical bowel preparation (MBP) in conjunction with oral antibiotics (OABs) have been shown to reduce SSI rates, while it is still unclear which OABs to use and how this can be implemented in practice. Introduction of OABs in conjunction with MBP in colorectal surgery is feasible and might potentially lead to lower rates of SSI, as well as altering the community structure of the faecal microbiome.