Transcriptional profiles of immature neurons in aged human hippocampus track Alzheimer's pathology and cognitive resilience

Following files submitted: 1. adultgc_filtered.RDS : Filtered (after QC) seurat object of adult granule cell subset of 24 samples. 2. fetal_raw.RDS : Unfiltered seurat object of fetal samples (n=3). 3. fetal_filtered.RDS : Filtered (after QC) seurat object of fetal samples (n=3). 4. Functions.R : Helper functions written for running scripts. 5. Fig1_script.Rmd : Script to reproduce analysis in Figure 1 and its supplementaries. 6. Fig2_script.Rmd : Script to reproduce analysis in Figure 2 and its supplementaries. 7. Fig3_script.Rmd : Script to reproduce analysis in Figure 3 and its supplementaries. 8. Fig4_script.Rmd : Script to reproduce analysis in Figure 4 and its supplementaries. 9. Fig5_script.Rmd : Script to reproduce analysis in Figure 5 and its supplementaries. 10. Fig6_script.Rmd : Script to reproduce analysis in Figure 6 and its supplementaries. 11. Fig6_script_CellPhoneDB.py : Script to reproduce CellPhoneDB analysis in Fig6. 12. scANVI_script_mouse.ipynb : Script to reproduce scANVI analysis for mouse dataset published in Hochgerner et al 2018. 13. scANVI_script_human.ipynb : Script to reproduce scANVI analysis for human dataset produced in this study (n=24).