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Microarray whole transcriptome profiling of LPS (Escherichia coli O111:B4) treated BV-2 Cells

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NIAID Data Ecosystem2026-03-12 收录
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A common in vitro model for evaluating anti-inflammatory agents is use of lipopolysaccharide (LPS) , a cell wall endotoxic component from gram negative bacteria which evokes a deadly cytokine storm associated with septicemia, septic shock and multi organ failure. In this study , we investigate whole transcriptome changes occurring at 24 hours of incubation with LPS (1ug/ml) in BV2 murine microglia cells. Microarrays were acquired for mRNAs and long intergenic non-coding RNA transcripts using the GeneChip™ MOGENE 2.1ST ARRAY Arrays by Affymetrix Inc. BV-2 Cells treated with LPS or control

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2021-07-25
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