Effect of Lira treatment on heart in obese mice

C57BL/6 Male mice were treated with high fat diet at the age of 8 weeks and continue the diet for 16 weeks(4 mo) and then injected them with placebo/drug for 1 week before scarifice. Their were sacrifised at the age of 6 months. Drug: Lira is used to reduce morbidity and mortality due to obesity and its effect on heart. 10 C57BL/6 Male mice under high fat diet for 16 weeks treated with eithe Placebo/drug were chosen for the microarray analysis. Heart from each mouse was disected and the left ventricle was used for TRNA extraction.