Synthesis of the New Mannosidase Inhibitors, Diversity-Oriented 5-Substituted Swainsonine Analogues, via Stereoselective Mannich Reaction
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5α-Substituted swainsonine analogues were synthesized by Mannich reaction of an in situ generated (−)-swainsonine iminium ion intermediate. 5α-Substituted swainsonine analogues were epimerized to their 5β-isomers in protic solvent.
创建时间:
2004-03-04



