首页/数据集/RNA-seq of the human melanoma cell-line A375P treated with the BRAF inhibitor PLX4720 and a DMSO control

RNA-seq of the human melanoma cell-line A375P treated with the BRAF inhibitor PLX4720 and a DMSO control

ChEBI2019-08-07 更新2026-07-12 收录

黑色素瘤靶向治疗

转录组药物响应

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-7453 数据链接链接失效反馈

官方服务：

资源简介：

RNA-seq of the human melanoma cell-line A375P treated with the BRAF inhibitor PLX4720 and a DMSO control

应用场景：

创建时间：

2019-08-07

黑色素瘤靶向治疗

肿瘤耐药机制

FDA-approved BRAF inhibitors produce high response rates and improve overall survival in patients with BRAF V600E/K mutant melanoma, but are linked to pathologies associated with paradoxical ERK1/2 ac

NIAID Data Ecosystem70

Effect of ribociclib on breast cancer cells

乳腺癌药物机制

转录组药物响应

To study mechanisms underlying response to ribociclib. Overall design: Examination of breast cancer cell transcriptome following treatment with ribociclib (600 nM).

NIAID Data Ecosystem50

The Novel Gamma Secretase Inhibitor RO4929097 Reduces the Tumor Initiating Potential of Melanoma

黑色素瘤靶向治疗

NOTCH信号通路分析

Several reports have demonstrated a role for aberrant NOTCH signaling in melanoma genesis and progression, prompting us to explore if targeting this pathway is a valid therapeutic approach against mel

NIAID Data Ecosystem40

Transcriptional profiling of M. tuberculosis treated with DG167 and INH

结核分枝杆菌药物机制

转录组药物响应

We report that combined treatment with both DG167 and INH activates a cellular response associated with loss of persistence and induction of cidality that is distinct from the cellular response induce

NIAID Data Ecosystem70

Suppression of adaptive responses to targeted cancer therapy by transcriptional repression [RNA-seq]. Homo sapiens

肿瘤耐药机制

转录组药物响应

Large-scale genomic profiling efforts have facilitated the characterization of molecular alterations in cancers and aided the development of targeted kinase inhibitors for a wide array of cancer types

NIAID Data Ecosystem50

RNA-seq of the human melanoma cell-line A375P treated with the BRAF inhibitor PLX4720 and a DMSO control

资源简介：

相关数据集