Pharmacophore Hybridization To Discover Novel Topoisomerase II Poisons with Promising Antiproliferative Activity
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https://figshare.com/articles/dataset/Pharmacophore_Hybridization_To_Discover_Novel_Topoisomerase_II_Poisons_with_Promising_Antiproliferative_Activity/5588449
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资源简介：
We used a pharmacophore
hybridization strategy to combine key structural
elements of merbarone and etoposide and generated new type II topoisomerase
(topoII) poisons. This first set of hybrid topoII poisons shows promising
antiproliferative activity on human cancer cells, endorsing their
further exploration for anticancer drug discovery.
创建时间：
2017-11-09
