EVI1 in acute myeloid leukemia triggers metabolic reprogramming associated with leukemogenesis
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE118096
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资源简介：
Overexpression of Ecotropic Virus Integration site 1 protein homolog (EVI1) in adults and children with mixed lineage leukemia-rearrangement acute myeloid leukemia (MLL-r AML) has a very poor prognosis. We used an extracellular flux analyze to examine metabolic changes during leukemia development in a mouse model of MLL-r AML expressing high levels of Evi1 (Evi1+). Two groups analyzed: 1) Whole MLL-AF9 leukemia cells from WT mice, 2) Whole MLL-AF9 leukemia cells from Evi1 Tg mice.
创建时间：
2018-08-05
