Crystal Structure of PI3Kalpha in complex with fragment 14
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Crystal Structure of PI3Kalpha in complex with fragment 14 Descriptor: 4,6-dimethylpyridin-2-amine, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Authors: Gabelli, S.B, Vogelstein, B, Miller, M.S, Amzel, L.M. Deposit date: 2016-08-09 Release date: 2017-02-15 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (3.52 Å) Cite: Identification of allosteric binding sites for PI3K alpha oncogenic mutant specific inhibitor design. Bioorg. Med. Chem., 25, 2017
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2016-08-09
