The chromatin remodeler BRG1 is altered in the Letmd1 KO mice. We performed chromatin IP for BRG1 from BAT of wild-type (WT) versus Letmd1 KO mice. Overall design: ChIP-seq from WT vs. Letmd1 KO brown
ChIP-seq for endogenously C-terminally tagged Setd5 with a 3xFLAG-HA tag. For each replicate of 100 million ESCs were harvested and cross linked in 1.5mM EGS and 1.5% PFA digested with MNase and mildl
The hypothalamus is crucial for regulating essential bodily functions, including energy balance. It is an exceedingly complex and heterogeneous brain region that contains a variety of neuronal systems
Otx2 has been shown to be non cell autonomously required for photoreceptor cell survival in the adult mouse RPE. This study aims to identify Otx2 DNA binding profile in both RPE and neural retina to i